Product Type: Inhibitor
CAS No.: 396129-53-6
MolecularFormula: C17H12N4
Molecular Weight: 272,3
Source: Synthetic
Purity: ≥98% (HPLC)
Solubility: Soluble to 100 mM in DMSO
Appearance: Yellow to brown solid
PubChem CID: 447966
Scientific Background: LY364947 is a potent and selective inhibitor of TGF-β type-1 receptor kinase. Specifically, it inhibits TGF-β signaling and gene transcription. LY364947 is cell permeable and ATP-competitive.
References: 1. Vogt J., Traynor R., & Sapkota G.P. (2011) Cell. Signal. 23(11): 1831–1842.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.