Lysophosphatidic Acid, Sodium Salt, CAS 22556-62-3

Autophagy inhibitor

Product Type: Inhibitor

CAS No.: 22556-62-3

MolecularFormula: C21H41O7P*Na

Molecular Weight: 458,5

Source: Synthetic

Purity: >98% (TLC); NMR (Conforms)

Solubility: Soluble in DMSO (1 mg/ml) and warm water (10 mg/ml).

Appearance: White powder.

PubChem CID: 5311263

Scientific Background: Oleoyl-lysophosphatidic acid is an endogenous agonist of the lysophospholipid receptors LPA1 and LPA2. It has been shown to induce cellular functions such as cell proliferation and migration, and ICAM-1, IL-8 and MCP-1 expression. Lysophosphatidic acid has also been observed to inhibit autophagy in cells under starvation conditions by inhibiting autophagosome formation.

References: 1. van Corven E.J., et al. (1992) Biochem J. 281(Pt 1): 163-9.2. Chang C.L., et al. (2007) Autophagy. 3(3): 268-70.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSIH-403-5MG
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SIH-403-5MG
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK