Product Description: Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin (HY-128914) and its derivative cytotoxic molecule[1]. Mal-PEG2-acid is also a PROTAC linker that can be used in the synthesis of PROTACs.
Applications: Cancer-programmed cell death
Formula: C11H15NO6
References: [1]Zhao, Yongxin, et al. Cytotoxin molecule, conjugate and preparation method and application thereof. Faming Zhuanli Shenqing (2019), CN 109912683 A 20190621.
CAS Number: 1374666-32-6
Molecular Weight: 257.24
Compound Purity: 97.0
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: ADC Linker;PROTAC Linkers