English
MAN1B1 antibody (3C2)
MAN1B1 antibody (3C2)
Artikelnummer
GTX03413-100
Verpackungseinheit
100 μl
Hersteller
GeneTex
Verfügbarkeit:
wird geladen...
Preis wird geladen...
Clone Name: 3C2
Light Chain: Kappa
Application Note: WB: 1:500-1:1000. ICC/IF: 1:100. IHC-P: 1:200. IP: 1:10-1:100. ELISA: 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 80
Specificity/Sensitivity: We do not recommend use of this product for Mouse.,Knockdown/Knockout validation was supported by references (PMID: 26205822).
Form: Liquid
Buffer (with preservative): Tris-Glycine pH 7.5, 0.15M NaCl, 0.05% sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Dec 2011]
Uniprot ID: Q9UKM7
Antigen Species: Human
Immunogen: Full length human recombinant ERManI [Swiss-Prot# Q9UKM7].
Purification: Protein G purified
Conjugation: Unconjugated
Full Name: mannosidase alpha class 1B member 1
Light Chain: Kappa
Application Note: WB: 1:500-1:1000. ICC/IF: 1:100. IHC-P: 1:200. IP: 1:10-1:100. ELISA: 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 80
Specificity/Sensitivity: We do not recommend use of this product for Mouse.,Knockdown/Knockout validation was supported by references (PMID: 26205822).
Form: Liquid
Buffer (with preservative): Tris-Glycine pH 7.5, 0.15M NaCl, 0.05% sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Dec 2011]
Uniprot ID: Q9UKM7
Antigen Species: Human
Immunogen: Full length human recombinant ERManI [Swiss-Prot# Q9UKM7].
Purification: Protein G purified
Conjugation: Unconjugated
Full Name: mannosidase alpha class 1B member 1
| Artikelnummer | GTX03413-100 |
|---|---|
| Hersteller | GeneTex |
| Hersteller Artikelnummer | GTX03413-100 |
| Green Labware | Nein |
| Verpackungseinheit | 100 μl |
| Mengeneinheit | STK |
| Reaktivität | Human |
| Klonalität | Monoclonal |
| Methode | Immunofluorescence, Immunohistochemistry (paraffin), Immunoprecipitation, Western Blotting, ELISA, Immunocytochemistry |
| Isotyp | IgG1 |
| Human Gene ID | 11253 |
| Wirt | Mouse |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
Verwandte Artikel
Markieren Sie die Artikel, um Sie dem Warenkorb hinzuzufügen oder
Immer für Sie da
Gernot Ensinger, M.Sc.
Laurent Haze
