MAP3K8 antibody (HL2118)

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Clone Name: HL2118

Light Chain: Kappa

Application Note: WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 53

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 2 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011]

Uniprot ID: P41279

Antigen Species: Human

Immunogen: Recombinant fragmemt of human MAP3K8

Purification: Affinity purified by Protein A.

Conjugation: Unconjugated

Full Name: mitogen-activated protein kinase kinase kinase 8

• Artikelnummer: GTX638090-S-25
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX638090-S-25
• Verpackungseinheit: 25 μl
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine)
• Klonalität: Recombinant
• Methode: Immunohistochemistry (paraffin), Western Blotting
• Isotyp: IgG
• Human Gene ID: 1326
• Wirt: Rabbit
• Konjugat: Unconjugated