MBOAT2 (C-Term) Polyclonal Antibody

Formulation: 500 µl of peptide affinity-purified polyclonal antibody

Immunogen: Peptide from the C-terminal region of human MBOAT2

Shelf life (days): 1095

Notes: Membrane-bound O-acyltransferase 2 (MBOAT2) is a membrane-spanning enzyme of the MBOAT family encoded by the LPCAT4 gene in humans.{27302} It contains multiple transmembrane domains and has two active site residues, an asparagine and a histidine, in common with other MBOAT family members.{27302} MBOAT2 is expressed in mouse epididymis, brain, testis, and ovary and is localized to the endoplasmic reticulum in CHO cells.{35639} MBOAT2 has acyltransferase activities, with a preference for using oleoyl-coenzyme A (oleoyl-CoA) as an acyl donor and lysophosphatidylethanolamine (Item No. 25844), lysophosphatidic acid, or lysophosphatidylcholine (Item No. 24331) as acyl acceptors at the sn-2 position.{27123} MBOAT2 expression is increased in the epithelia of patient-derived pancreatic ductal adenocarcinoma (PDAC) tumor tissue and this expression is inversely correlated with patient survival.{56207} In contrast, decreased expression of serum circular MBOAT2 RNA levels are found in patients with hypertrophic cardiomyopathy.{56208} Cayman’s MBOAT2 (C-Term) Polyclonal Antibody can be used for flow cytometry and immunofluorescence applications.

• Artikelnummer: CAY15646-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 15646-500
• Green Labware: Nein
• Verpackungseinheit: 1 ea (500 µl)
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Polyclonal
• Methode: Immunofluorescence, Flow Cytometry
• Wirt: Rabbit