MC-Gly-Gly-Phe-Gly-GABA-Exatecan, CAS 1599439-52-7

Product Description: MC-Gly-Gly-Phe-Gly-GABA-Exatecan is an agent linker conjugate for ADC, with an inhibitor for Topoisomerase Exatecan (HY-13631) with IC50 of 22 μM. MC-Gly-Gly-Phe-Gly-GABA-Exatecan targets various antibodies, exhibits cytotoxic and antitumor efficacy in vitro and in vivo[1][2].

Applications: Cancer-programmed cell death

Formula: C53H58FN9O12

References: [1]Hettmann T, et al., Anti-her3 antibody-drug conjugate. Patent WO2015155998/[2]Ogitani Y, et al., Wide application of a novel topoisomerase I inhibitor-based drug conjugation technology. Bioorg Med Chem Lett. 2016 Oct 15;26(20):5069-5072.

CAS Number: 1599439-52-7

Molecular Weight: 1032.08

Compound Purity: 99.72

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Drug-Linker Conjugates for ADC;Topoisomerase

• Artikelnummer: MEXHY-160649-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-160649-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK