MC-Val-Cit-PAB-MMAF, CAS 863971-17-9

Product Description: MC-Val-Cit-PAB-MMAF (Vc-MMAF) is a drug-linker conjugate for ADC by using the tubulin inhibitor, MMAF (HY-15579), linked via cathepsin cleavable MC-Val-Cit-PAB (HY-78738). MC-Val-Cit-PAB-MMAF shows antitumor activity[1].

Applications: Cancer-programmed cell death

Formula: C68H103N11O16

References: [1]Cheng X, et al. MORAb-202, an Antibody-Drug Conjugate Utilizing Humanized Anti-human FRα Farletuzumab and the Microtubule-targeting Agent Eribulin, has Potent Antitumor Activity. Mol Cancer Ther. 2018 Dec;17(12):2665-2675.

CAS Number: 863971-17-9

Molecular Weight: 1330.61

Compound Purity: 98.16

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)/H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Drug-Linker Conjugates for ADC

• Artikelnummer: MEXHY-112786-50
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-112786-50
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK