Product Description: MCC-DM1 is a agent-Linker Conjugates for ADC such as Anti-CD22-MCC-DM1. MCC-DM1 can be detected in rat and human plasma, feces, and other tissues[1][2].
Applications: Cancer-programmed cell death
Formula: C47H64ClN5O13S
References: [1]Liu Y, et al. LC-MS/MS method for the simultaneous determination of Lys-MCC-DM1, MCC-DM1 and DM1 as potential intracellular catabolites of the antibody-drug conjugate trastuzumab emtansine (T-DM1). J Pharm Biomed Anal. 2017 Apr 15;137:170-177. /[2]Manu Lopus, et al. Antibody-DM1 conjugates as cancer therapeutics. Cancer Lett. 2011 Aug 28;307(2):113-8.
CAS Number: 1100692-14-5
Molecular Weight: 974.55
Compound Purity: 99.72
Research Area: Cancer
Solubility: DMSO : 190 mg/mL (ultrasonic)
Target: Drug-Linker Conjugates for ADC