MCM7 antibody (AT118H7)

Clone Name: AT118H7

Light Chain: Kappa

Calculated MW: 81

Form: Liquid

Buffer (with preservative): PBS, 10% Glycerol, 0.02% Sodium azide.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Uniprot ID: P33993

Antigen Species: Human

Immunogen: The clone AT118H7 is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human MCM9 protein.

Purification: Protein A Purified

Conjugation: Unconjugated

Full Name: minichromosome maintenance complex component 7

• Artikelnummer: GTX57715-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX57715-100
• Green Labware: Nein
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Western Blotting, Immunocytochemistry
• Isotyp: IgG1
• Human Gene ID: 4176
• Wirt: Mouse