MCM7 antibody

Application Note: WB: 1:1000-1:5000. ICC/IF: 1:200-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 81

Form: Liquid

Buffer (with preservative): PBS, 50% Glycerol, no preservative.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Uniprot ID: P33993

Antigen Species: Human

Immunogen: Purified His6-tagged human MCM7 protein encompassing 562 -719 amino acids

Purification: Purified IgG

Conjugation: Unconjugated

Full Name: minichromosome maintenance complex component 7

• Artikelnummer: GTX00894-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX00894-100
• Green Labware: Nein
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus), Hamster
• Klonalität: Polyclonal
• Methode: Immunofluorescence, Immunoprecipitation, Western Blotting, Immunocytochemistry, Chromatin Immunoprecipitation (ChIP), Fluorescence-Activated Cell Sorting (FACS)
• Isotyp: IgG
• Human Gene ID: 4176
• Wirt: Rabbit