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MCM7 antibody (MSVA-507R) HistoMAX™
MCM7 antibody (MSVA-507R) HistoMAX™
Artikelnummer
GTX04444-500
Verpackungseinheit
500 μl
Hersteller
GeneTex
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Clone Name: MSVA-507R
Product Description: This antibody was validated on 76 different Normal Tissues by IHC-P.
Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 81
Positive Control: Colon: A strong nuclear MCM7 immunostaining should be seen in virtually all crypt base cells.
Negative Control: Colon: MCM7 immunostaining should be largely absent in surface epithelial cells and in most stroma cells.
Form: Liquid
Buffer (with preservative): 10mM PBS, 0.05% BSA (Please contact us for sodium azide-free or sodium azide and BSA-free format), 0.05% sodium azide.
Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Uniprot ID: P33993
Antigen Species: Human
Immunogen: Recombinant human MCM7 protein fragment (aa195-319)
Purification: Protein A/G purified
Conjugation: Unconjugated
Full Name: minichromosome maintenance complex component 7
Product Description: This antibody was validated on 76 different Normal Tissues by IHC-P.
Go to Normal Tissue GalleryGo to Cancer Tissue Gallery
Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 81
Positive Control: Colon: A strong nuclear MCM7 immunostaining should be seen in virtually all crypt base cells.
Negative Control: Colon: MCM7 immunostaining should be largely absent in surface epithelial cells and in most stroma cells.
Form: Liquid
Buffer (with preservative): 10mM PBS, 0.05% BSA (Please contact us for sodium azide-free or sodium azide and BSA-free format), 0.05% sodium azide.
Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Uniprot ID: P33993
Antigen Species: Human
Immunogen: Recombinant human MCM7 protein fragment (aa195-319)
Purification: Protein A/G purified
Conjugation: Unconjugated
Full Name: minichromosome maintenance complex component 7
| Artikelnummer | GTX04444-500 |
|---|---|
| Hersteller | GeneTex |
| Hersteller Artikelnummer | GTX04444-500 |
| Green Labware | Nein |
| Verpackungseinheit | 500 μl |
| Mengeneinheit | STK |
| Reaktivität | Human |
| Klonalität | Monoclonal |
| Methode | Immunohistochemistry (paraffin) |
| Isotyp | IgG |
| Human Gene ID | 4176 |
| Wirt | Rabbit |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
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