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Encompassing Amino Acids: 78-162
Applications: Useful for DNA methylation and DNA binding studies.
Description: Human recombinant Methyl CpG binding Protein 2 (Rett syndrome) (MECP2), GenBank Accession #NM_004992), a.a. 78-162 with N-terminal GST-tag, MW= 36 kDa, expressed in an E. coli expression system.
Format: Aqueous buffer solution
Formulation: 45 mM Tris-HCl, pH 8.0, 124 mM NaCl, 2.2 mM KCl, 18 mM glutathione, 10% glycerol and 3 mM DTT.
Genbank: NM_004992
Storage Stability: At least 6 months at -80°C.
Tags: N-terminal GST-tag
Uniprot: P51608
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Amir, R.E., et al. (1999). Nat. Genet. 23 (2): 185-8.
2. Lewis, J.D., et al. (1992). Cell 69 (6): 905-14.
3. Chahrour M, et al. (2008). Science 320 (5880): 1224-9.