Target Synonym: MSLN;MPF;SMRP
Storage: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Background: This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Immunogen: Recombinant fusion protein of human Mesothelin
Dilution: WB 1:500-1:2000
Calculated MW: 67kDa/68kDa/71kDa
Observed MW: 45KDa
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