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Metnase (SETMAR), FLAG-tag Recombinant
Metnase (SETMAR), FLAG-tag Recombinant
Artikelnummer
BPS51018
Verpackungseinheit
20 µg
Hersteller
BPS Bioscience
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Encompassing Amino Acids: 27-684(end)
Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Background: SETMAR or SET domain and mariner transposase fusion gene is a nonhomologous end-joining repair protein that regulates genomic integration of exogenous DNA by opening chromatin and facilitating joining of DNA ends. SETMAR has histone methyltransferase activity and methylates 'Lys-4' and 'Lys-36' of histone H3. SETMAR also has DNA nicking activity and may play a role in DNA repair. Human Pso4 forms a stable complex with SETMAR that regulates Metnase function in DNA repair. SETMAR has sequence-specific DNA-binding activity and recognizes the 19-mer core of the 5'-terminal inverted repeats (TIRs) of the Hsmar1 element.
Description: Human Metnase (SETMAR, or SET domain and mariner transposase fusion), GenBank Accession No. NM_006515, a.a. 27-684(end), with N-terminal FLAG-tag, MW=76 kDa, expressed in FreeStyle 293-F cells.
Format: Aqueous buffer solution
Formulation: 45 mM Tris-HCl, pH 8.0, 124 mM NaCl, 2.4 mM KCl, 3 mM DTT, 90 ?g/ml FLAG peptide, and 10% glyceroll
Genbank: NM_006515
Host Cell Line: Freestyle 293-F cells
Storage Stability: At least 6 months at -80°C.
Tags: N-terminal FLAG-tag
Uniprot: Q53H47
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Wray J. et al., Blood 114(9), 1852-1858 (2009).
2. Williamson E.A. et al., Nucleic Acids Res. 36 (18), 5822-5831 (2008).
Encompassing Amino Acids: 27-684(end)
Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Background: SETMAR or SET domain and mariner transposase fusion gene is a nonhomologous end-joining repair protein that regulates genomic integration of exogenous DNA by opening chromatin and facilitating joining of DNA ends. SETMAR has histone methyltransferase activity and methylates 'Lys-4' and 'Lys-36' of histone H3. SETMAR also has DNA nicking activity and may play a role in DNA repair. Human Pso4 forms a stable complex with SETMAR that regulates Metnase function in DNA repair. SETMAR has sequence-specific DNA-binding activity and recognizes the 19-mer core of the 5'-terminal inverted repeats (TIRs) of the Hsmar1 element.
Description: Human Metnase (SETMAR, or SET domain and mariner transposase fusion), GenBank Accession No. NM_006515, a.a. 27-684(end), with N-terminal FLAG-tag, MW=76 kDa, expressed in FreeStyle 293-F cells.
Format: Aqueous buffer solution
Formulation: 45 mM Tris-HCl, pH 8.0, 124 mM NaCl, 2.4 mM KCl, 3 mM DTT, 90 ?g/ml FLAG peptide, and 10% glyceroll
Genbank: NM_006515
Host Cell Line: Freestyle 293-F cells
Storage Stability: At least 6 months at -80°C.
Tags: N-terminal FLAG-tag
Uniprot: Q53H47
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Wray J. et al., Blood 114(9), 1852-1858 (2009).
2. Williamson E.A. et al., Nucleic Acids Res. 36 (18), 5822-5831 (2008).
| Artikelnummer | BPS51018 |
|---|---|
| Hersteller | BPS Bioscience |
| Hersteller Artikelnummer | 51018 |
| Green Labware | Nein |
| Verpackungseinheit | 20 µg |
| Mengeneinheit | STK |
| Wirt | Human |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
Immer für Sie da
Gernot Ensinger, M.Sc.
Laurent Haze
