MHC II (HLA-DRA)(169-1B5.2), 1mg/mL

Description: This antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kDa alpha (heavy) chain and a 28 kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4 T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Mus musculus (mouse)

Clone: 169-1B5.2

Entrez Gene ID: 3122

Immunogen: Human peripheral blood leukocytes

Expected AB Applications: IF (published for clone)

Verified AB Applications: Flow (verified)

Z-Antibody Applications: Flow (verified)/IF (published)

• Artikelnummer: BTMBNUM1096-50
• Hersteller: Biotium
• Hersteller Artikelnummer: BNUM1096-50
• Green Labware: Nein
• Verpackungseinheit: 50 uL
• Mengeneinheit: STK
• Reaktivität: Human, Cat (Feline), Cow (Bovine)
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Flow Cytometry
• Isotyp: IgG2b kappa
• Wirt: Mouse