Abbreviation: MICU1
Target Synonym: CALC;CBARA1;EFHA3;MPXPS;MICU1
Conjugation: Unconjugated
UNIProt ID: Q9BPX6
Background: This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2013]
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human MICU1
Dilution: WB 1:500-1:2000