MJN110, CAS 1438416-21-7

Product Description: MJN110 is an orally active and selective monoacylglycerol lipase (MAGL) inhibitor with IC50s of 9.1 nM and 2.1 nM for hMAGL and 2-arachidonoylglycerol (2-AG), respectively[1]. MJN110 produces opioid-sparing effects and displays strong antihyperalgesic activity[2].

Applications: Neuroscience-Neuromodulation

Formula: C22H21Cl2N3O4

References: [1]Wilkerson JL, et al. The Selective Monoacylglycerol Lipase Inhibitor MJN110 Produces Opioid-Sparing Effects in a Mouse Neuropathic Pain Model. J Pharmacol Exp Ther. 2016 Apr;357(1):145-56./[2]Niphakis MJ, et al. Evaluation of NHS carbamates as a potent and selective class of endocannabinoid hydrolase inhibitors. ACS Chem Neurosci. 2013 Sep 18;4(9):1322-32.

CAS Number: 1438416-21-7

Molecular Weight: 462.33

Compound Purity: 99.49

Research Area: Neurological Disease

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: MAGL

• Artikelnummer: MEXHY-117474-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-117474-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK