MMAF intermediate 2, CAS 864238-20-0

Product Description: MMAF intermediate 2 is an intermediate for the synthesis of MMAF (HY-15579). MMAF (Monomethylauristatin F) is a potent inhibitor of tubulin polymerization and the cytotoxic (ADC Cytotoxin) component of classic antibody drug conjugates (ADCs), such as Vorsetuzumab mafodotin and SGN-CD19A[1].

Applications: Cancer-programmed cell death

Formula: C19H29ClN2O4

References: [1]Lee JW, et al. EphA2 targeted chemotherapy using an antibody drug conjugate in endometrial carcinoma. Clin Cancer Res. 2010 May 1;16(9):2562-70. [Content Brief]

CAS Number: 864238-20-0

Molecular Weight: 384.90

Compound Purity: 99.77

Research Area: cancer

Solubility: 10 mM in DMSO

Target: ADC Cytotoxin

• Artikelnummer: MEXHY-79254-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-79254-10.1
• Verpackungseinheit: 10mM/1mL
• Mengeneinheit: STK