Mouse anti-AGPS Purified, clone AGPS-03 (Monoclonal)

Clone Number: AGPS-03

Immunogen: recombinant human AGPS (amino acids 158-384)

Concentration: 1 mg/ml

Format: Purified by protein-A affinity chromatography.

Storage buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Additional info: AGPS (alkylglycerone phosphate synthase), is an enzyme that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetone phosphate (acyl-DHAP) is converted to alkyl-DHAP by addition of a long chain alcohol and removal of a long-chain acid anion. The protein is localized to the inner side of the peroxisomal membrane and requires FAD as a cofactor. Mutations in AGPS gene have been associated with type 3 of rhizomelic chondrodysplasia punctata (RCDP3), and Zellweger syndrome. Higher expression of AGPS was observed in BCR/ABL positive leukemias and it was also described to be associated with higher risk of relapse.SpecificityThe antibody AGR3.4 recognizes the PLMII epitope of AGR3 (AG3) and AGR2 (AG2) proteins (19-20 kDa); secreted cytoplasmic proteins which can serve as markers of carcinogenesis.Application detailsFlow cytometry: Recommended dilution: 1-4 μg/ml. Intracellular staining.
Western blotting: Recommended dilution: 1-2 μg/ml.

• Artikelnummer: SANMON23006
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON23006
• Verpackungseinheit: 0,1 mg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Western Blotting, Flow Cytometry
• Isotyp: IgG2a
• Wirt: Mouse
• Konjugat: Unconjugated