Mouse anti-Blood Group A (CD173), clone HE-10 (monoclonal)

Clone Number: HE-10

Immunogen: mixture of erythrocytes of blood group A1 and a glycoprotein fraction isolated from the salvia of secretors with blood group A of human origin

Concentration: 100 ug/ml

Storage buffer: PBS with 0.02% sodium azide

Additional info: HE-10 preferably reacts with determinants of chain A type 3 and 4 and chain H type 3 and 4, but not with type 1 and 2 chain structures. It is not reactive with immunodominant A trisaccharide. Increased expression of this antigen has been observed on some tumor tissues such as gastric carcinomas, urothelial carcinomas, and colon carcinomas. HE-10 does not react with normal tissue sections of donors with blood group B and 0 but it reacts specifically with malignant tissues in these individuals. HE-10 is applicable for red cell agglutination, tissue staining and immunofluorescence tests.

References: Němec M. et al. Vox Sang 52:125-8 (1987)/Vanák J. et al. Neoplasma 36(4): 479-487 (1989)/Tichý, M. et al. Neoplasma 37(4): 451-459 (1990)

• Artikelnummer: SANMON9816
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON9816
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunohistochemistry (frozen), Immunohistochemistry (paraffin), Flow Cytometry, Functional Assay
• Isotyp: IgM-k
• Wirt: Mouse