Rabbit anti-CD117, clone YR145

Clone Number: YR145

Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers

Concentration: n/a

Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide

Additional info: CD117, c-kit is a tyrosine kinase receptor found on interstitial cells of Cajal, germ cells, bone marrow stem cells, melanocytes, breast epithelium and mast cells. This receptor is found on a wide variety of tumor cells (follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, breast; malignant melanoma, endodermal sinus tumor, and small cell carcinoma) but has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi’s sarcoma, and tumors of smooth muscle origin.

References: Sircar K, et al. AM J Surg Pathol 23(4):377-389,1999/Miettinen M et al. Am J Surg Pathol 24(2):211-222, 2000/Miettinen M. et al. Am J Surg Pathol 23(9): 1109-1118

• Artikelnummer: SANMON-RTU1058
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON-RTU1058
• Verpackungseinheit: 7 ml
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG
• Wirt: Rabbit
• Konjugat: Unconjugated