Mouse anti-CD11a, clone CRIS-3 (Monoclonal)

Clone Number: CRIS-3

Immunogen: stimulated human leucocytes

Concentration: 100 ug/ml

Storage buffer: PBS with 0.02% sodium azide

Additional info: Cris-3 reacts with CD11a, a transmembrane molecule with 1145 amino acid residues and a MW of 180 kDa. CD11a is expressed on lymphocytes, granulocytes, monocytes and macrophages. Levels on memory T-cells ten to increase. CD11a plays a key role in mediating leukocyte adhesion to endothelium during inflammatory responses through binding to ICAM-1 (CD54). Other ligands are ICAM-2 and ICAM-3. It is also involved in many other T-cell functions and immune phenomena. When paired with CD18, it forms the integrin alphaLbeta2 heterodimer also called LFA-1. LFA-1 is chiefly responsible for lymphocyte adhesion.

References: Reinherz et. al., EL. Leukocyte Typing II. New York: Springer-Verlag (1985)/Jain et al. Folia Neuropathol 47(1), 33-42 (2009)

• Artikelnummer: SANMON2103
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON2103
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunohistochemistry (frozen), Flow Cytometry
• Isotyp: IgG2b
• Wirt: Mouse