Mouse anti-CD11b, clone EBS-CD-010 (Monoclonal)

Clone Number: EBS-CD-010

Immunogen: human neutrophils.

Concentration: 100 ug/ml

Storage buffer: PBS with 0.02% sodium azide

Additional info: Integrin αM (also designated complement component receptor 3 α-chain; CD11b (p170); macrophage antigen α polypeptide; cell surface glycoprotein Mac-1 α-subunit; CR3 α-chain; MAC1A; MO1A and ITGAM) is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an α-chain and a β-chain. Integrin αM combines with Integrin β2 (CD18) to form a leukocyte-specific integrin referred to as macrophage receptor-1 (Mac-1) or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin αM-β2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.

References: Beekhuizen H, et al., J Immunol. 145(2):510-8 (1990)/Argenbright LW et al., J Leukoc Biol. 49(3):253-7 (1991)/Zhou L, et al. J Biol Chem. 269(25):17075-9 (1994)

• Artikelnummer: SANMON9919
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON9919
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunohistochemistry (frozen), Flow Cytometry
• Isotyp: IgG1-k
• Wirt: Mouse