Mouse anti-CD13, clone EBS-CD-012 (Monoclonal)

Clone Number: EBS-CD-012

Immunogen: human AML cells

Concentration: 100 ug/ml

Storage buffer: PBS with 0.02% sodium azide

Additional info: EBS-CD-12 recognizes an extracellular epitope on an integral membrane glycoprotein of 150 kDa, identified as CD13 (also known as aminopeptidase-N). CD13 is present on most cells of myeloid origin including granulocytes, monocytes, mast cells, and GM-progenitor cells. It is also expressed by the majority of AML, CML in myeloid blast crisis, and in a smaller fraction of lymphoid leukemias. CD13 is also present on fibroblasts; endothelial cells, epithelial cells from renal proximal tubules and intestinal brush border, bone marrow stromal cells, osteoclasts, and cells lining bile duct canaliculi. CD13 plays a role in metabolism of biologically active peptides, in phagocytosis, and in bactericidal/tumoricidal activities. It also serves as a receptor for human coronaviruses (hCoV) and human cytomegalovirus (hCMV).

References: Favaloro EJ, et al., Exp Hematol. 13:1695-701 (1993)/Favaloro EJ, et al., Clin Chim Acta.220(1):81-90 (1993)/Lachance C., et al. J Virol. 72(8):6511-9. (1998)

• Artikelnummer: SANMON9921
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON9921
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunohistochemistry (frozen), Immunohistochemistry (paraffin), Western Blotting, Flow Cytometry
• Isotyp: IgG1-k
• Wirt: Mouse
• Konjugat: Unconjugated