Mouse anti-CD15/FUTU4/Lex, clone FR4A5 (Monoclonal)

Clone Number: FR4A5

Immunogen: RAJI cells. Splenocytes were fused with mouse myeloma X63Ag8/653 cells

Concentration: 100 ug/ml

Storage buffer: PBS with 0.02% sodium azide

Additional info: FR4A5 reacts with CD15 (220 kDa). CD15 contains the pentasaccharide lacto-n-fucopentaose III and plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance. It is also expressed on a wide variety of other tumor cells including myeloid leukemia, breast, colorectal, and lung cancer cells. Cross reactivity has been observed with Glcα1-6glcα1-4Glc, Tn, blood group H1, and maltose.

References: Manimala J.C. et al. Glycobiology. 17(8): 17C-23C (2007)/Gildersleeve J. et al. Glycobiology. 18(0): 746 (2008)

• Artikelnummer: SANMON9833
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON9833
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunohistochemistry (frozen), Flow Cytometry
• Isotyp: IgM-k
• Wirt: Mouse
• Konjugat: Unconjugated