Mouse anti-CD158b, clone GL183 (Monoclonal)

Clone Number: GL183

Conjugate: Purified

Immunogen: NK cell clone E57

Concentration: 1.0 mg/ml

Storage buffer: PBS

Additional info: Mouse anti Human CD158b antibody, clone GL183 recognizes human Killer cell immunoglobulin-like receptor 2DL3, also known as CD158b, KIR-023GB, MHC class I NK cell receptor, p58 natural killer cell receptor clone CL-6 or Natural killer-associated transcript 2. CD158b is a 341 amino acid, ~58 kDa single pass type-1 transmembrane glycoprotein containing two Ig-like C2-type domains. expressed by a subset of NK cells.This antibody also recognizes a ~50 kDa molecule in some NK clones, which is highly homologous to p58.2 in the extracellular domain, but has a shorter cytoplasmic tail (Moretta et al. 1985). Both molecules are members of the newly described natural killer cell receptor family.CD158b functions as a receptor specific for HLA Class I molecules, including Cw3 and related HLA-C alleles. Mouse anti Human CD158b antibody, clone GL183 can restore the lysis by human NK clones of otherwise lysis protected targets expressing Cw3.

• Artikelnummer: SANMON4061
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON4061
• Green Labware: Nein
• Verpackungseinheit: 0,2 mg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunoprecipitation, Flow Cytometry
• Isotyp: IgG1
• Wirt: Mouse