Mouse anti-CD45RO Monoclonal Antibody, Purified (UCHL-1)

Stock Concentration: 1000 µg/ml

Conjugate Type: Unconjugated

Buffer: Phosphate Buffered Saline (PBS) with 0.09% Sodium Azide, BSA-Free

Shelf Life: 1 year from date of receipt

Protein ID: NP_563578.2

Uniprot ID: P08575

Background: CD45RO is also known as protein tyrosine phosphatase receptor type C (PTPRC). It is a protein tyrosine phosphatase required for T-cell activation through the antigen receptor. CD45RO acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, CD45RO recruits and dephosphorylates SKAP1 and FYN. It also dephosphorylates LYN, and thereby modulates LYN activity (By similarity)[taken from UniProtKB (Entry: P08575)].

Immunogen: Cultured T-cells from an IL-2-dependent T-cell line (CA1)

• Artikelnummer: BEYA500-020ACF
• Hersteller: Bethyl Laboratories
• Hersteller Artikelnummer: A500-020ACF
• Verpackungseinheit: 100 µl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Western Blotting, Flow Cytometry, Immunohistochemistry, Immunocytochemistry
• Isotyp: Whole IgG
• Human Gene ID: 5788
• Wirt: Mouse
• Konjugat: Unconjugated