Clone Number: NK-1
Immunogen: preparation of HSB-2 T cell line
Concentration: 100 ug/ul
Storage buffer: PBS with 0.02% sodium azide
Additional info: NK-1 reacts with CD57, a 110 kDa antigen present on the surface of human NK-cells and Tcell subsets. In adult peripheral blood 20% of mononuclear cells are positive. Other positive tissues include peripheral nerves (myelin-associated glycoprotein) and prostate. Anti-CD57 also stains neuroendocrine cells and their derived tumors, including carcinoid tumor and medulloblastomas. Anti-CD57 can also be useful in separating type B3 thymoma from thymic carcinoma when combined with a panel that includes antibodies against GLUT1, CD5, and CEA.
References: Abo T et al J. Immunol 127:1024 (1981)/Abo T et al. J Immunol 129(4):1752-7 (1982)/Abo T et al. J Immunol 129(4):1758-61 (1982)