Mouse anti-CD59, clone MEM-43 (Monoclonal)

Clone Number: MEM-43

Immunogen: Thymocytes and T lymphocytes

Concentration: 1 mg/ml

Storage buffer: Phosphate buffered saline (PBS) solution with 15 mM sodium azide

Additional info: CD59 (protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC). It is thus the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 associates with C5b-8 complex and thereby counteracts appropriate formation of cytolytic pore within the plasma membrane. CD59 is also an low-affinity ligand of human CD2 and causes T cell costimulation.

• Artikelnummer: SANMON1136
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON1136
• Green Labware: Nein
• Verpackungseinheit: 0,1 mg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin), Immunoprecipitation, Flow Cytometry
• Isotyp: IgG2a
• Wirt: Mouse