Mouse anti-CD68 Recombinant Monoclonal Antibody, Purified (KP-1)

Stock Concentration: 1000 µg/ml

Conjugate Type: Unconjugated

Buffer: Phosphate Buffered Saline (PBS) with 0.09% Sodium Azide, BSA-Free

Shelf Life: 1 year from date of receipt

Protein ID: NP_001242.2

Uniprot ID: P34810

Background: CD68 is a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins.CD68 is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages [taken from NCBI Entrez Gene (Gene ID: 968)].

Immunogen: Lysosomal fraction of human lung macrophages

• Artikelnummer: BEYA500-018ACF
• Hersteller: Bethyl Laboratories
• Hersteller Artikelnummer: A500-018ACF
• Green Labware: Nein
• Verpackungseinheit: 100 µl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Flow Cytometry, Immunohistochemistry
• Isotyp: Whole IgG
• Human Gene ID: 968
• Wirt: Mouse