Clone Number: BF12
Immunogen: CLL cells
Concentration: 100 ug/ml
Storage buffer: PBS with 0.02% sodium azide
Additional info: BF12 recognizes 40 kDa CD7, a member of the immunoglobulin gene superfamily and expressed on the majority of immature and mature T-lymphocytes, and T-cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B-cells and on malignant B-cells. CD7 associates directly with phosphoinositol 3’-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.
References: Wang, MY et. al, Bone Marrow Transplant. 9(5): 319-23 (1992)