Clone Number: LN-1
Immunogen: nuclei from pokeweed mitrogen-stimulated PBL
Concentration: 100 ug/ml
Storage buffer: PBS with 0.02% sodium azide
Additional info: LN-1 reacts with CDw75, a neuraminidase sensitive cell surface sialoglycan which is present on the cell membrane and cytoplasm of germininal center B-cells and derived lymphomas. CDw75 has a function in cell adhesion and is the ligand for CD22. LN-1 reacts with RBC precursors in bone marrow, ductal and ciliated epithelial cells of kidney, breast, prostate, pancreas, lung, and with gioblastomas and astrocytoma’s, and also Reed Sternberg cells in Hodgkin’s disease.
References: Epstein AL et. al. J of Immunology 133: 1028-1036 (1984)