Mouse anti-CD94, clone DX22 (Monoclonal)

Clone Number: DX22

Conjugate: Purified

Immunogen: Natural killer cell line.

Concentration: 1.0 mg/ml

Storage buffer: PBS with 0.09% sodium azide

Additional info: Mouse anti Human CD94 antibody, clone DX22 recognizes human Natural killer cells antigen CD94, also known as KLRD1, Killer cell lectin-like receptor, subfamily D, member 1, CD94, KP43 and NK cell receptor. CD94 is a 179 amino acid single pass type II transmembrane glycoprotein with a predicted molecular mass of ~20.5 kDa. There are 3 isoforms of CD94 derived by alternative splicing.CD94 is expressed on natural killer (NK) cells and a subset of T lymphocytes.CD94 is found to associate with NKG2 to form a heterodimer, involved in the inhibition of cell mediated cytotoxicity against cells bearing appropriate MHC class I allotypes.Mouse anti Human CD94 antibody, clone DX22 is reported to inhibit the binding of CD94 to HLA-E (Braud et al. 1998) and HLA-G (Söderström. et al. 1997).

• Artikelnummer: SANMON4069
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON4069
• Green Labware: Nein
• Verpackungseinheit: 0,2 mg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Flow Cytometry
• Isotyp: IgG1
• Wirt: Mouse