Clone Number: POH-1
Immunogen: recombinant human p34cdc2 fusion protein
Concentration: 100 ug/ml
Storage buffer: PBS with 0.02% sodium azide
Additional info: POH-1 detects the three bands within the 34kDa region corresponding to the p34 protein cyclin dependent kinase 1 (cdk1) and its cleavage products. It is positive in immunoblotting on HeLa cell lysate and negative on fibroblast (LEP strain) cell lysate. A cdc2 homolog, the cdk2 protein kinase, does not react with POH-1. Activated cdk1 / p34cdc2 performs specific functions during mitosis, including nuclear envelope breakdown and chromosome condensation.
References: Lukáš, J, et al. Eur. J. Biochem., 207: 169-176 (1992)