Mouse anti-CDw17, clone EBS-CD-014 (Monoclonal)

Clone Number: EBS-CD-014

Immunogen: beta-2 microglobulin associated proteins from a detergent lysate of human PBL

Concentration: 100 ug/ml

Storage buffer: PBS with 0.02% sodium azide

Additional info: CDw17 is an intermediate glycosphingolipid from the metabolism of higher gangliosides that localizes to sphingolipid-sterol rafts. CDw17 is found on monocytes, granulocytes, basophils, platelets, a subset of peripheral B-cells (CD19+) and tonsil dendritic cells. It is rapidly down regulated on activated granulocytes and is upregulated on IL-2 activated T-lymphocytes. CDw17 binds to bacteria and may function in phagocytosis. It may also be involved in angiogenesis. Aberrant levels of glycosphingolipids are a feature of cancer cells and may influence integrin clustering and internalization.

References: Knapp W. Leukocyte Typing IV, Oxford Univ. Press, (1989)

• Artikelnummer: SANMON9924
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON9924
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunohistochemistry (frozen), Flow Cytometry
• Isotyp: IgM-k
• Wirt: Mouse