Rabbit anti-Cytokeratin 5 & Mouse anti-Cytokeratin 14, clone EP1601Y & LL002

Clone Number: EP1601Y & LL002

Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers

Concentration: n/a

Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide

Additional info: Cytokeratin 5 is an intermediate filament protein of 58 kD amongst the cytokeratin family. It is a type II (basic) cytokeratin. Antibodies to this protein identify basal cells of squamous and glandular epithelia, myoepithelia, and mesothelium.1 Cytokeratin 14 is a 50 kD polypeptide found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells.1 Anti-cytokeratin 5 has been useful in the differential diagnosis of metastatic carcinoma in the pleura versus epithelial mesothelioma.2 Anti-cytokeratin 14 has been demonstrated to be useful in differentiating squamous cell carcinomas from other epithelial tumors.3,4 Anti-Cytokeratin 5, along with anti-cytokeratin 14, has been found to have an application in identifying the basal-like phenotype of breast carcinoma.5

References: Dabbs DJ. Elsevier Saunders, 2014. Print. P. 212/Comin CE, et al. Am J Surg Pathol. 2007; 31:1139-48/Reis-Filho JS, et al. Appl Immunohistochem Mol Morphol. 2003; 11:1-8

• Artikelnummer: SANMON-RTU1220
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON-RTU1220
• Green Labware: Nein
• Verpackungseinheit: 7 ml
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG /IgG3
• Wirt: Mouse