Mouse anti-Cytokeratin 7, clone OV-TL 12/30

Clone Number: OV-TL 12/30

Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers

Concentration: n/a

Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide

Additional info: Anti-cytokeratin 7 reacts with proteins that are found in most ductal, glandular, transitional, and biliary duct epithelial cells. Cytokeratin 7 (CK7) labeling can help distinguish between lung,breast carcinomas, and urothelial carcinomas that typically stain positive, and colon and prostate carcinomas that typically lack CK7 expression.CK 7 is a common marker of primary lung adenocarcinomas (almost all cases) with a lower specificity since it is also observed in other primary lung carcinomas and non-pulmonary carcinomas.1 Anti-cytokeratin 7 has also been useful in the differential diagnosis of ovarian neoplasms.This antibody does not recognize intermediate filament proteins.

References: Jerome MV, et al. Histopathology. 2004; 45:125-34/Murray SK, et al. Am J Surg Pathol. 2004; 28:1154-62/Ramalingam P, et al. Ann Diagn Pathol. 2003; 7:112-9

• Artikelnummer: SANMON-RTU1074
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON-RTU1074
• Green Labware: Nein
• Verpackungseinheit: 7 ml
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG1-k
• Wirt: Mouse