Mouse anti Desmin, clone BS21 (Monoclonal)

Clone Number: BS21

Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers

Concentration: n/a

Format: Concentrate

Storage buffer: Tris Buffer, pH 7.2 with 0.03% Sodium Azide

Additional info: Desmin (DES), with 470-amino acid protein (about 52kDa), belongs to the intermediate filament family and Desmin is class III intermediate filaments found in muscle cells. Homopolymers of Desmin form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane.Mutations in Desmin are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.Desmin is also expressed in smooth muscle cells of both airways and alveolar ducts and Desmin is a load-bearing protein that stiffens the airways and consequently the lung and modulates airway contractile response.

• Artikelnummer: SANMON5158-1
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON5158-1
• Green Labware: Nein
• Verpackungseinheit: 1 ml
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (frozen), Immunohistochemistry (paraffin)
• Isotyp: IgG1
• Wirt: Mouse