Mouse anti-Desmin, clone D33

Clone Number: D33

Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers

Concentration: n/a

Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide

Additional info: Anti-desmin detects a protein that is expressed by cells of normal smooth, skeletal, and cardiac muscles. It has been suggested that desmin is primarily located at or near the periphery of Z lines in striated muscle fibrils. In smooth muscle, desmin interconnects cytoplasmic dense bodies with membrane bound dense plaques. Anti-desmin reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin.This antibody is used to demonstrate the myogenic components/derivation of tumors. Desmin can also be present in myofibroblasts and be focally positive in desmoid fibromatosis.

References: Kouloumenta A, Journal of Biological Chemistry. 2007; 282:35211-21/Altmannsberger M, et al. Am J Pathol 1985; 118:85-95/Debus E, et al. EMBO J. 1983; 2:2305-12

• Artikelnummer: SANMON-RTU1093
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON-RTU1093
• Green Labware: Nein
• Verpackungseinheit: 7 ml
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG1-k
• Wirt: Mouse