Mouse anti-Hu CD200R Purified, clone OX-108 (Monoclonal)

Clone Number: OX-108

Immunogen: Recombinant human CD200R

Concentration: 1 mg/ml

Format: Purified by protein-A affinity chromatography.

Storage buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Additional info: CD200R is a transmembrane glycoprotein, expressed on the surface of myeloid cells. Its interaction with CD200 leads in these cells to a downregulatory signal. This interaction may control myeloid function in a tissue-specific manner. Alternative splicing of CD200R gene results in multiple transcript variants. These isoforms may play a role in differentiation, e.g. regards tolerogenic dendritic cells. Besides myeloid cells, CD200R can be found also on a T cell subset.SpecificityThe mouse monoclonal antibody NP4D6 reacts with an extracellular epitope of CD203c, a transmembrane ectoenzyme expressed on basophils and mast cells, and overexpressed upon their activation.Application detailsFlow cytometry: Recommended dilution: 2-5 μg/ml.

• Artikelnummer: SANMON23137
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON23137
• Green Labware: Nein
• Verpackungseinheit: 0,1 mg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Flow Cytometry, Immunocytochemistry
• Isotyp: IgG1 kappa
• Wirt: Mouse