Mouse anti-Hu CD300e Purified, clone UP-H2 (Monoclonal)

Clone Number: UP-H2

Immunogen: CD300e-HA-transfected cells

Concentration: 1 mg/ml

Format: Purified by protein-A affinity chromatography.

Storage buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Additional info: CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.SpecificityThe mouse monoclonal antibody NKTA255 recognizes an extracellular epitope of CD305 / LAIR1, a 40 kDa type I transmembrane glycoprotein expressed on NK, T, and B cells, monocytes, dendritic cells, eosinophils, basophils, mast cells, CD34+ hematopoietic progenitor cells and thymocytes.Application detailsFlow cytometry: Recommended dilution: 1-4 μg/ml.

• Artikelnummer: SANMON23166
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON23166
• Verpackungseinheit: 0,1 mg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunoprecipitation, Western Blotting, Flow Cytometry
• Isotyp: IgG1 kappa
• Wirt: Mouse
• Konjugat: Unconjugated