Mouse anti Human CD25, conjugated with PE

Mouse anti Human CD25, conjugated with PE, Monoclonal, IgG1, Clone: ITYV
Artikelnummer
EXA0254
Verpackungseinheit
100 Tests
Hersteller
Exalpha Biologicals Inc

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Clone: ITYV.

Background: Identification of human receptor for Interleukin-2 (IL-2R) expressing the 55,000 M.W. surface antigen.

Immunogen: CD25=Derived from the hybridization of mouse NS-1 myeloma cells with spleen cells of BALB/c mice immunized with PHA-activated human T-lymphocytes.

Purification Method: Protein A/G Chromatography.

Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide and 0.2% carrier protein.

References: 1. A Monoclonal Antibody (Anti-Tac) Reactive with Activated and Functionally Mature Human T Cells. Uchiyama T., Broder S., Waldmann TA, 1981 J. Immunol.126,1393.

2. Direct Demonstration of the Identity of T Cell Growth Factor Binding Protein and the Tac Antigen. Robb RJ, Greene WC, J. Exp. Med. 1983,158;1332.

3. Patients with HIV infection have a reduced proportion of lymphocytes expressing the IL2 receptor p55 chain (TAC, CD25). Zola H., Koh L.Y., Mantzioris B.X., Rhodes D., Clin. Immunol. Immunopathol. 1991 Ap:59(1):16-25.

4. Spontaneous lymphocyte proliferation in HTLV-I/II infection reflects preferential activation of CD8 and CD16/56 cell subsets. Prince H.E., Weber D.M., Jensen E.R., Clin. Immunol. Immunopathol. 1991, May;58(3):419-30.

5. Defective clonogenic potential of CD8+ T lymphocytes in patients with AIDS. Expansion in vivo of a nonclonogenic CD3+ CD8+ DR+ CD25- T cell population. Pantaleo G., Keonig S., Baseler M., Lane H.C., Fauci A.S., J. Immunol. 1990 Mar ; 144(5):1696-704.

UniProt: P01589.

Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
Mehr Informationen
Artikelnummer EXA0254
Hersteller Exalpha Biologicals Inc
Hersteller Artikelnummer 0254
Green Labware Nein
Verpackungseinheit 100 Tests
Mengeneinheit PAK
Reaktivität Human
Klonalität Monoclonal
Methode Flow Cytometry
Isotyp IgG1
Wirt Mouse
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