Mouse anti-Human CD33, clone PWS44

Clone Number: PWS44

Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers

Concentration: n/a

Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide

Additional info: CD33, also known as gp67 or SIGLEC-3, is a 67 kDa glycosylated transmembrane protein that is a member of the sialic acid-binding immunoglobulin-like lectin (siglec) family. Although the precise physiological function of CD33 is unknown, it may mediate cell to cell adhesion and modulate inflammatory and immune response. In normal tissue, anti-CD33 labels myeloid cells (especially myeloid precursors), liver Kupffer cells, lung alveolar macrophages, and placental syncytiotrophoblasts. In neoplastic tissue, anti-CD33 is useful for the identification of acute myeloid leukemia.

References: Freeman SD, et al. Blood. 1995; 85:2005-12/Laszlo GS, et al. Oncotarget. 2016; 7:43281-94/Crocker, PR et al. Biochem Soc Symp 2002; 69:83-96

• Artikelnummer: SANMON-RTU1252
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON-RTU1252
• Verpackungseinheit: 7 ml
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG2b
• Wirt: Mouse
• Konjugat: Unconjugated