Clone Number: E11
Immunogen: Human acute monocytic leukaemia cells
Concentration: IgG 1 mg/ml
Format: Purified
Storage buffer: PBS with <0.1% sodium azide
Additional info: Mouse anti Human CD35 antibody, clone E11 recognizes complement receptor type 1, also known as CD35 or the C3b/C4b receptor. CD35 a single chain, type I single pass transmembrane glycoprotein which exists in four allotypic forms (A,B,C,D) of ~190 kDa, ~220 kDa, ~160 kDa and ~250 kDa respectively (Khera et al. 2009).CD35 is expressed by granulocytes, monocytes, B cells and some T cells. Functionally, CD35 acts as a receptor for the C3b component of complement.
References: Hogg N et al. Eur J Immunol 1984; 14: 236-43/Birmingham DJ et al. J Immunol 1996; 157: 2586-92/Sopper S et al. Cytometry 1997; 29: 351-62