Mouse anti-Human CD47, clone 1/1A4(Monoclonal)

Clone Number: 1/1A4

Immunogen: Human erythrocytes

Concentration: IgG 1 mg/ml

Format: Purified

Storage buffer: PBS with <0.1% sodium azide

Additional info: Mouse anti Human CD47 antibody, clone 1/1A4 recognizes human CD47, also known as integrin-associated protein, a 50kDa glycoprotein expressed on all haematopoietic cell lines, epithelial cells, endothelial cells, fibroblasts and many tumour cell lines. CD47 is involved in several cellular processes including regulation of T cell and dendritic cell activation, regulation of neutrophil (PMN) chemotaxis, caspase-independent apoptosis, and may act as a signal transducer in the regulation of cation fluxes across cell membranes. CD47 has been identified as a ligand for the inhibitory macrophage receptor known as signal regulatory protein alpha (SIRPalpha) and as a receptor for thrombospondin-1.

References: Waclavicek M et al. J Immunol 1997; 159: 5345-54

• Artikelnummer: SANMON10321
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON10321
• Green Labware: Nein
• Verpackungseinheit: 0,2 mg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (frozen), Immunoprecipitation, Flow Cytometry
• Isotyp: IgG2b
• Wirt: Mouse