Mouse anti Human CD7, conjugated with FITC

Mouse anti Human CD7, conjugated with FITC, Monoclonal, IgG2a, Clone: MG34
Artikelnummer
EXA0072
Verpackungseinheit
100 Tests
Hersteller
Exalpha Biologicals Inc

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Clone: MG34.

Background: Identification of human T lymphocytes in multiple stages of T cell development, including a major subset of mature peripheral T cells. CD7 antigen is often increased on T leukemic cells. The CD7 molecule is a 40,000 M.W. surface antigen that is expressed on T-Lymphoid and myeloid precursors in fetal liver and bone marrow.

Immunogen: CD7=Derived from the hybridization of mouse P3-X63-Ag8.653 myeloma cells with spleen cells of BALB/c mice immunized with T-acute lymphoblastic leukemia (T-ALL) cells.

Purification Method: Protein A/G Chromatography.

Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide and 0.2% carrier protein.

References: 1. Isolation and characterization of the genomic human CD7 gene: structural similarity with the murine Thy-1 gene. Schanberg, L.E., Fleener, D.E., Kurtzberg, J., Haynes, B.F., Kaufman, R.E.; Proc. Natl. Acad. Sci. USA , 1991 Jan 1;88(2):603-7.

2. Identification of novel B-lineage cells in human fetal bone marrow that coexpress CD7. Grumayer, E.R., Griesinger, F., Hummell, D.S., Brunning, R.D., Kersey, J.H.; Blood, 1991 Jan ; 77(1):64-8.

3. Genuine CD7 expression in acute leukemic and lymphoblastic lymphoma. Osada, H., Emi, N., Ueda, R., Seto, M., Koike, K., Suchi, T., Kojima, S., Obata, Y., Takahashi, T.; Leuk. Res. 1990;14(10):869-77.

4. Inhibition of alloresponsive naive and memory T cells by CD7 and CD25 antibodies and by cyclosporine. Akbar, A.N., Amlot, P.L., Ivory,K., Timms, A., Janossy, G.; Transplantation, 1990 No;50(5):823-9.

5. Comparsion of outcome, clinical, laboratory, and immunological features in 164 children and adults with T-ALL. Garand, R., Vannier, J.P., Bene, M.C., Faure, G., Favre, M., Bernard, A,. Leukemia,1990 No;4(11):739-44.

UniProt: P09564 (Human).

Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
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Artikelnummer EXA0072
Hersteller Exalpha Biologicals Inc
Hersteller Artikelnummer 0072
Green Labware Nein
Verpackungseinheit 100 Tests
Mengeneinheit PAK
Reaktivität Human
Klonalität Monoclonal
Methode Flow Cytometry
Isotyp IgG2a
Wirt Mouse
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