Mouse anti-Human MAdCAM-1, clone 17F5 (Monoclonal)

Clone Number: 17F5

Immunogen: Recombinant soluble MAdCAM-1-fc fusion protein

Concentration: IgG 1 mg/ml

Format: Purified

Storage buffer: PBS with <0.1% sodium azide

Additional info: Mouse anti Human MAdCAM-1 antibody, clone 17F5 recognizes human mucosal addressin cell adhesion molecule 1 (MAdCAM-1) a ~60 kDa transmembrane protein that belongs to the immunoglobulin superfamily. MAdCAM-1 is strongly expressed on mucosal lymphoid tissue and high endothelial venules of Peyer's patches. Human MAdCAM-1 interacts with the beta 7 integrin LPAM-1 (alpha4beta7), CD62L, and VLA-4 (alpha4beta1) and is involved in lymphocyte trafficking, Mouse anti Human MAdCAM-1 antibody, clone 17F5 recognizes the mucin domain of MAdCAM-1. This antibody does not block the function of MAdCAM-1 (Leung, E. et al. 2004).

References: Leung E et al. Immunol Cell Biol 1996; 74: 490-6/Leung E et al. Immunol Cell Biol 2004; 82: 400-9/Guerra-Perez N et al. J Immunol 2015; 194: 2415-23

• Artikelnummer: SANMON10340
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON10340
• Green Labware: Nein
• Verpackungseinheit: 0,2 mg
• Mengeneinheit: STK
• Reaktivität: Human, Various species
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin), Western Blotting, ELISA, Flow Cytometry
• Isotyp: IgG1
• Wirt: Mouse