Clone Number: NAP-03
Immunogen: Peptide corresponding to aa 196-212 of human NTAL coupled to KLH.
Concentration: 1 mg/ml
Storage buffer: Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Additional info: NTAL (non-T cell activation linker), also known as LAB (linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells and macrophages. It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells. However, in mast cells, NTAL also contributes to some activation processes, partially overlapping with LAT function.