Mouse anti-p16INK4a Recombinant Monoclonal Antibody (BC42)

Stock Concentration: 100 µg/ml

Conjugate Type: Unconjugated

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide

Shelf Life: 1 year from date of receipt

Protein ID: NP_000068.1

Uniprot ID: P42771

Background: p16INK4a is a negative regulator of CDK4 and CDK6 kinase activity and cell cycle progression. p16INK4a regulates the cell cycle by inhibiting cyclin/CDK complex formation and the phosphorylation of the retinoblastoma protein (pRb). The gene which encodes p16INK4a, CDKN2A, is frequently mutated or deleted in a wide variety of tumors and is known to be an important tumor suppressor gene. The CDKN2A gene also generates a distinct transcript variant and protein, p14ARF, from an alternate open reading frame (ARF).

Immunogen: Human p16 INK4A

• Artikelnummer: BEYA700-292
• Hersteller: Bethyl Laboratories
• Hersteller Artikelnummer: A700-292
• Green Labware: Nein
• Verpackungseinheit: 100 µl (50+ tests)
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Western Blotting, Flow Cytometry, Immunohistochemistry, Immunocytochemistry
• Isotyp: Whole IgG
• Human Gene ID: 1029
• Wirt: Mouse